Ever wondered how our carboxygenator precisely works within the SCINUS bioreactor NG? We get that question more often, so today we’re excited to share the science behind it, step by step:
𝗣𝗿𝗲𝗰𝗶𝘀𝗲 𝗚𝗮𝘀 𝗖𝗼𝗻𝘁𝗿𝗼𝗹: The carboxygenator is a patented oxygenation system that’s all about maintaining the ideal gas environment for your cell culture.
𝗜𝗻𝘁𝗲𝗴𝗿𝗮𝘁𝗲𝗱 𝗦𝗲𝗻𝘀𝗼𝗿𝘀: Oxygen and pH levels are continuously monitored by advanced sensors within the SCINUS culture bag. This real-time data is crucial for maintaining optimal conditions.
𝗗𝗮𝘁𝗮 𝗧𝗿𝗮𝗻𝘀𝗺𝗶𝘀𝘀𝗶𝗼𝗻: As we continue in the process, this data is transmitted to the controller software of the SCINUS cabinet through transmitters built into the rocking expansion platform.
𝗔𝘂𝘁𝗼𝗺𝗮𝘁𝗲𝗱 𝗖𝗼𝗻𝘁𝗿𝗼𝗹: Our controller software takes the wheel from here. It ensures that the pre-defined culture environment is maintained by controlling the addition of gases, thanks to the data received.
𝗚𝗮𝘀 𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻: The addition of gases takes place through gas-permeable tubing in the perfusion loop. This crucial step ensures a seamless and precise process for maintaining the optimal gas environment within the culture bag.
𝗖𝗼𝗻𝘁𝗶𝗻𝘂𝗼𝘂𝘀 𝗙𝗲𝗲𝗱𝗯𝗮𝗰𝗸-𝗟𝗼𝗼𝗽: A continuous feedback loop between the culture bag and the carboxygenator guarantees that setpoints are maintained within minimal bandwidths.
𝗡𝗼 𝗛𝗲𝗮𝗱𝘀𝗽𝗮𝗰𝗲 𝗥𝗲𝗾𝘂𝗶𝗿𝗲𝗱: With our carboxygenator, we can provide your cells with the oxygen they need without the use of a headspace, resulting in a homogenized culture.
𝗠𝗶𝗻𝗶𝗺𝗶𝘇𝗲𝗱 𝗦𝗵𝗲𝗮𝗿: What’s more, this process minimizes any additional shear on your cells as there is no air-liquid interface during the rocking process.
At SCINUS, we’re proud to deliver innovation that empowers your research and cell culture experiments. If you’re as excited about this as we are, let’s keep the conversation going. Reach out, and let’s explore the possibilities together!
A continuous feedback loop between the culture bag and the carboxygenator guarantees that oxygen and pH setpoints are maintained within minimal bandwidths.