Ever wondered how our carboxygenator precisely works within the SCINUS bioreactor NG?
We get that question more often, so today weโre excited to share the science behind it, step by step:
๐ฃ๐ฟ๐ฒ๐ฐ๐ถ๐๐ฒ ๐๐ฎ๐ ๐๐ผ๐ป๐๐ฟ๐ผ๐น: The carboxygenator is a patented oxygenation system thatโs all about maintaining the ideal gas environment for your cell culture.
๐๐ป๐๐ฒ๐ด๐ฟ๐ฎ๐๐ฒ๐ฑ ๐ฆ๐ฒ๐ป๐๐ผ๐ฟ๐: Oxygen and pH levels are continuously monitored by advanced sensors within the SCINUS culture bag. This real-time data is crucial for maintaining optimal conditions.
๐๐ฎ๐๐ฎ ๐ง๐ฟ๐ฎ๐ป๐๐บ๐ถ๐๐๐ถ๐ผ๐ป: As we continue in the process, this data is transmitted to the controller software of the SCINUS cabinet through transmitters built into the rocking expansion platform.
๐๐๐๐ผ๐บ๐ฎ๐๐ฒ๐ฑ ๐๐ผ๐ป๐๐ฟ๐ผ๐น: Our controller software takes the wheel from here. It ensures that the pre-defined culture environment is maintained by controlling the addition of gases, thanks to the data received.
๐๐ฎ๐ ๐๐ป๐๐ฟ๐ผ๐ฑ๐๐ฐ๐๐ถ๐ผ๐ป: The addition of gases takes place through gas-permeable tubing in the perfusion loop. This crucial step ensures a seamless and precise process for maintaining the optimal gas environment within the culture bag.
๐๐ผ๐ป๐๐ถ๐ป๐๐ผ๐๐ ๐๐ฒ๐ฒ๐ฑ๐ฏ๐ฎ๐ฐ๐ธ-๐๐ผ๐ผ๐ฝ: A continuous feedback loop between the culture bag and the carboxygenator guarantees that setpoints are maintained within minimal bandwidths.
๐ก๐ผ ๐๐ฒ๐ฎ๐ฑ๐๐ฝ๐ฎ๐ฐ๐ฒ ๐ฅ๐ฒ๐พ๐๐ถ๐ฟ๐ฒ๐ฑ: With our carboxygenator, we can provide your cells with the oxygen they need without the use of a headspace, resulting in a homogenized culture.
๐ ๐ถ๐ป๐ถ๐บ๐ถ๐๐ฒ๐ฑ ๐ฆ๐ต๐ฒ๐ฎ๐ฟ: Whatโs more, this process minimizes any additional shear on your cells as there is no air-liquid interface during the rocking process.
At SCINUS, weโre proud to deliver innovation that empowers your research and cell culture experiments. If youโre as excited about this as we are, letโs keep the conversation going. Reach out, and letโs explore the possibilities together!
A continuous feedback loop between the culture bag and the carboxygenator guarantees that oxygen and pH setpoints are maintained within minimal bandwidths.